Amoxicillin-clavulanate, also known as Augmentin, is a very commonly used antibiotic. However, resistance continues to occur and often leads to the ineffectiveness of this antibiotic. The following article discusses the mechanisms of resistance against amoxicillin-clavulanate in E.coli.[1]


  1. A. Ortega, J. Oteo, M. Aranzamendi-Zaldumbide, R.M. Bartolomé, G. Bou, E. Cercenado, M.C. Conejo, J.J. González-López, M. Marín, L. Martínez-Martínez, M. Merino, F. Navarro, A. Oliver, . Pascual, A. Rivera, J. Rodríguez-Baño, I. Weber, B. Aracil, and J. Campos, "Spanish Multicenter Study of the Epidemiology and Mechanisms of Amoxicillin-Clavulanate Resistance in Escherichia coli", Antimicrobial Agents and Chemotherapy, vol. 56, pp. 3576-3581, 2012. http://dx.doi.org/10.1128/AAC.06393-11