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Clindamycin and Macrolides share many of the same resistance genes. The following article discusses this and the impact on treatment options[1]

References

  1. K. Waites, C. Johnson, B. Gray, K. Edwards, M. Crain, and W. Benjamin, "Use of clindamycin disks To detect macrolide resistance mediated by ermB and mefE in Streptococcus pneumoniae isolates from adults and children.", Journal of clinical microbiology, 2000. http://www.ncbi.nlm.nih.gov/pubmed/10790089