Clindamycin and Macrolides share many of the same resistance genes. The following article discusses this and the impact on treatment options[1]
References
- K. Waites, C. Johnson, B. Gray, K. Edwards, M. Crain, and W. Benjamin, "Use of clindamycin disks To detect macrolide resistance mediated by ermB and mefE in Streptococcus pneumoniae isolates from adults and children.", Journal of clinical microbiology, 2000. http://www.ncbi.nlm.nih.gov/pubmed/10790089